Symptom persistence and biomarkers in post-COVID-19/chronic fatigue syndrome

Franziska Legler presented her findings from a prospective observational cohort study in PCS and ME/CFS post COVID-19. PCS patients with moderate to severe fatigue continued to be significantly impaired in a follow-up of up to 20 months post infection. 106 patients were categorised into two groups, with those fulfilling the CCC diagnostic criteria for ME/CFS being worse off throughout the follow-up period. Correlation analysis revealed reduced hand grip strength at baseline as a viable indicator for continued symptom persistence and severity throughout the follow-up.