ME/CFS Research Foundation Logo

Federal Ministry of Education and Research (BMBF)

Federal Government

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Kapelle-Ufer 1
10117 Berlin
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Research projects
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Research projects

Analysis of Blood Immune Cell Transcriptomes by Single-Cell RNA Sequencing (scRNA-seq)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anna Aschenbrenner
Organisations:
Charité – University Medicine Berlin,University Clinic Bonn,German Center for Neurodegenerative Diseases (DZNE)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Hemic and lymphatic system dysfunction, General
Analysis of Differences in Plasma Proteins Using Mass Spectrometry
Project status:
Ongoing
Country:
Germany
Principal investigator:
Markus Ralser
Organisations:
Charité – University Medicine Berlin
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
General
Analysis of Serum/Plasma Markers and Changes in Cellular Composition and Activation of Blood Cells
Project status:
Ongoing
Country:
Germany
Principal investigator:
Birgit Sawitzki
Organisations:
Charité – University Medicine Berlin,Berlin Institute of Health at Charité (BIH)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
General
Autoantibody-induced Transcriptome and Proteome as Biomarkers
Project status:
Ongoing
Country:
Germany
Principal investigator:
Gabriela Riemekasten
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Luebeck
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM),Charité – University Medicine Berlin,University Clinic Schleswig-Holstein (UKSH) - Luebeck,Max Delbrück Center (MDC),Technical University of Munich (TUM)
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, General
COVID-19 Research Infrastructure Platform for Children and Adolescents (coverCHILD)
Project status:
Completed
Country:
Germany
Principal investigator:
Reinhard Berner, Ulrike Ravens-Sieberer
Organisations:
University Clinic Dresden,University Hospital rechts der Isar (MRI TUM),University Medical Center Hamburg-Eppendorf (UKE),Technical University of Munich (TUM)
Research period:
2022-09
to 2023-12
Research types:
Epidemiological research
Research areas:
General
COVIDOM: Longterm Morbidity of SARS-CoV-2 Infection and COVID-19 Disease - Consequences for Health Status and Quality of Life (NAPKON-POP)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Stefan Schreiber
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Kiel
Research period:
2020-11
to 2030-12
Research types:
Epidemiological research
Research areas:
General
Characterisation of brain function and vascular pathology with a focus on autonomic dysfunctions during sleep
Project status:
Ongoing
Country:
Germany
Principal investigator:
Robert Goeder
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Kiel
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Clinic and granulocytes
Project status:
Ongoing
Country:
Germany
Principal investigator:
Alexander Dejaco
Organisations:
University Clinic Regensburg
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Cardiovascular system dysfunction, General
Clinic, HDL proteome, and AI
Project status:
Ongoing
Country:
Germany
Principal investigator:
Elisabeth Schieffer
Organisations:
University Clinic Giessen and Marburg
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction
Clinical and immunological phenotyping and analysis of EBV autoantigens and autoantigens
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM),Technical University of Munich (TUM)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Clinical and immunological phenotyping, analysis of autoantigens and T and B cell communication
Project status:
Ongoing
Country:
Germany
Principal investigator:
Birgit Sawitzki
Organisations:
Charité – University Medicine Berlin,Berlin Institute of Health at Charité (BIH)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Clinical characterisation for biomarker discovery
Project status:
Ongoing
Country:
Germany
Principal investigator:
Helena Radbruch
Organisations:
Charité – University Medicine Berlin
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction
Clinical characterisation, integrative morphological and functional studies of organ perfusion and biomarkers in patients with ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Wolfram Doehner
Organisations:
Charité – University Medicine Berlin,Berlin Institute of Health at Charité (BIH)
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Musculoskeletal system dysfunction, Nervous system dysfunction, Nutritional and metabolic system dysfunction, Cardiovascular system dysfunction
Development and analysis of a SARS-CoV-2-induced golden hamster animal model for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Michael Muehlebach
Organisations:
Paul-Ehrlich-Institute (PEI)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction, General
Development and analysis of a SARS-CoV-2-induced mouse model for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Gregor Ebert
Organisations:
Helmholtz Munich
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction
EBV, SARS-CoV-2, HSV Mimicry Epitopes and Autoantibodies
Project status:
Ongoing
Country:
Germany
Principal investigator:
Franziska Sotzny
Organisations:
University Hospital rechts der Isar (MRI TUM),Charité – University Medicine Berlin,Technical University of Munich (TUM),Helmholtz Munich
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction, General
Endothelial Peripheral Arterial Tonometry (EndoPAT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin,Berlin School of Mind and Brain
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Evaluation of retinal vascular analysis as a diagnostic marker in post-infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christoph Schmaderer
Organisations:
University Hospital rechts der Isar (MRI TUM)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Functional autoantibodies against G-protein-coupled receptors in patients with ME/CFS (FAME)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Immune system dysfunction
Harmonisation and standardisation of the diagnosis of PEM in ME/CFS patients
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM),Technical University of Munich (TUM)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
General
Harmonised clinical phenotyping and biological signatures
Project status:
Ongoing
Country:
Germany
Principal investigator:
Martina Seifert
Organisations:
Charité – University Medicine Berlin
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction, General
Hyperbaric High Pressure Oxygen Therapy (HBOT) in Post-COVID Syndrome and ME/​CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
2023-07
to 2025-08
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Immune Aberrations in Post-Infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anna Aschenbrenner
Organisations:
Charité – University Medicine Berlin,University Clinic Bonn,German Center for Neurodegenerative Diseases (DZNE)
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Immune profiling and blood morphology analyses
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christian Puta
Organisations:
University Clinic Jena,Friedrich Schiller University Jena
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Immune system dysfunction, Musculoskeletal system dysfunction, Nervous system dysfunction
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS (IA-PACS-CFS)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Harald Pruess
Organisations:
Charité – University Medicine Berlin,German Center for Neurodegenerative Diseases (DZNE)
Research period:
2023-10
to 2025-02
Research types:
Clinical research
Research areas:
Immune system dysfunction
Integrative data analyses of human and animal model samples for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Volker Bruns
Organisations:
Fraunhofer Institute for Integrated Circuits (IIS)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction, General
Integrative transcriptome analyses of human and animal model samples for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Emanuel Wyler
Organisations:
Max Delbrück Center (MDC)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction, General
Investigation of PEM and ME/CFS-associated changes in tryptophan metabolism at the host and microbiome level
Project status:
Ongoing
Country:
Germany
Principal investigator:
Silvio Waschina
Organisations:
Kiel University (CAU)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Nutritional and metabolic system dysfunction, Digestive system dysfunction
Investigation of PEM and ME/CFS-associated tryptophan metabotypes
Project status:
Ongoing
Country:
Germany
Principal investigator:
Konrad Aden
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Kiel,Kiel University (CAU)
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Nutritional and metabolic system dysfunction
Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS) (PoCoVIT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christiana Franke
Organisations:
Charité – University Medicine Berlin
Research period:
2023-10
to 2025-03
Research types:
Clinical research
Research areas:
Immune system dysfunction, Nervous system dysfunction
Mitochondrial Dysfunction and Metabolic Changes
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, Nutritional and metabolic system dysfunction
Mobile sleep studies in adolescents
Project status:
Ongoing
Country:
Germany
Principal investigator:
Insa Wolf
Organisations:
Fraunhofer Institute for Digital Media Technology (IDMT)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Multimodal characterisation of brain function and blood flow, neuronal metabolism and genetic risk structure
Project status:
Ongoing
Country:
Germany
Principal investigator:
Claudia Schilling
Organisations:
Central Institute of Mental Health (CIMH)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Optical Coherence Tomography Angiography (OCT-A) and Non-invasive Dynamic Vessel Analysis (DVA)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin,Berlin School of Mind and Brain,Max Delbrück Center (MDC)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Raman spectroscopic signatures of blood cells
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anuradha Ramoji
Organisations:
Leibniz Institute of Photonic Technology
Research period:
2024-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Musculoskeletal system dysfunction
Repeat Immunoadsorption Post Covid ME/​CFS (RIA)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
2022-08
to 2025-01
Research types:
Clinical research
Research areas:
Immune system dysfunction
Structural and Functional MRI Studies and Accompanying Arterial Spin Labeling (ASL)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin,Berlin School of Mind and Brain,Max Delbrück Center (MDC)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome (VERI-LONG)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Judith Bellmann-Strobl
Organisations:
Charité – University Medicine Berlin,Max Delbrück Center (MDC)
Research period:
2023-06
to 2025-04
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction