G protein-coupled receptor (GPCR) autoantibodies
Description
G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors involved in signal transduction. They share a common structure and signal through heterotrimeric G-Proteins. GPCR-Autoantibodies are functional autoantibodies that bind to GPCR and activate second-messenger cascades in an uncontrolled manner. (Description adapted from: https://www.ncbi.nlm.nih.gov/mesh/68043562)
Research projects
6
Research types
13
Research networks
2
Working groups
9
People
16
Publications
21
Event items
1
Research projects
Autoantibody-induced Transcriptome and Proteome as Biomarkers
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Gabriela Riemekasten
Organisations:
University Clinic Schleswig-Holstein - Luebeck (UKSH)
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Uta Behrends
Organisations:
University Clinic Schleswig-Holstein - Luebeck (UKSH),Charité – University Medicine Berlin,University Hospital rechts der Isar (MRI TUM),Max Delbrück Center (MDC),Technical University of Munich (TUM)
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, General
Development of Diagnostic Tests to Detect Autoantibodies in CFS
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction
Observational Study of the Effect of Immunoadsorption (IA) in Patients < 18 Years of Age with ME/CFS with Evidence of Autoantibodies (BIAKI)
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Wolfgang Ries
Organisations:
DIAKO Hospital
Research period:
2023-11
to 2025-11
to 2025-11
Research types:
Clinical research
Research areas:
Immune system dysfunction
Repeat Immunoadsorption Post Covid ME/CFS (RIA)
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
2022-08
to 2025-01
to 2025-01
Research types:
Clinical research
Research areas:
Immune system dysfunction
unCOVer Erlangen - ME/CFS
Project status:
OngoingCountry:
GermanyPrincipal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
Not available
Research types:
Clinical research
Research areas:
Immune system dysfunction
Contact
ME/CFS Research Foundation
Ballindamm 27, 20095 Hamburg, Germany
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