Human herpesvirus 6 (HHV-6)
Description
Human Herpesvirus 6 (HHV-6) is a member of the roseolovirus genus of the Betaherpesvirales subfamily isolated from patients with AIDS and other lymphoproliferateive disorders. It infects and replicates in fresh and established lines of hematopoietic cells and cells of neural origin. It also appears to alter the activity of NK cells. HHV-6 antibodies are elevated in patients with AIDS, Sjögren's syndrome, sarcoidosis, ME/CFS, and certain malignancies. HHV-6A is the most common cause of exanthema subitum and has been implicated in encephalitis. When HHV-6 integrates into the host genome it is referred to as ciHVH-6. When such virus integration occurs into the germline it is referred to as iciHHV-6. Description adapted from: https://www.ncbi.nlm.nih.gov/mesh/68015654.
Research projects
4
Research types
5
Research networks
2
Working groups
4
People
8
Publications
6
Event items
0
Research projects
HHV-6 Mediated Mitochondrial Modulation and Its Association to ME/CFS
Project status:
Completed
Country:
Latvia, Germany
Principal investigator:
Bhupesh K. Prusty
Organisations:
Charité – University Medicine Berlin, University Clinic Erlangen, University of Wuerzburg, University of California San Diego, Riga Stradins University
Research period:
Not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction, General
Infectious Triggers and Mitochondrial Dysfunction in ME/CFS
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2021-08
to not available
to not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction
Understanding Potential Infectious Triggers and Mitochondrial Dysfunction in ME/CFS
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2025-01
to not available
to not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction
Virus infection and reactivation and gastrointestinal microbiome in ME/CFS
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Rig Haagmans
Organisations:
Amsterdam University Medical Center (Amsterdam UMC), Quadram Institute
Research period:
2025-08
to 2028-12
to 2028-12
Research types:
Basic research
Research areas:
Infections, Digestive system dysfunction