Clinical research - Interventional - Clinical trial phase II
Description
Interventional clinical research that follows successful phase I trials. For drugs or treatments already approved for other diseases, phase II usually follows successful case reports/series. It involves a larger number of individuals and evaluates treatment efficacy as well as potential side effects. Description adapted from: https://www.aerzteblatt.de/int/archive/article/64227.
Research projects
8
Research areas
18
Research networks
2
Working groups
7
People
25
Publications
10
Event items
2
Research projects
Cyclophosphamide in ME/CFS (CycloME)
Project status:
Completed
Country:
Norway
Principal investigator:
Øystein Fluge
Organisations:
Haukeland University Hospital
Research period:
2015-03
to 2019-12
to 2019-12
Research types:
Clinical research
Research areas:
Immune system dysfunction
Fecal microbiota transplant in chronic fatigue
Project status:
Ongoing
Country:
Norway
Principal investigator:
Rasmus Goll
Organisations:
The Arctic University of Norway
Research period:
2017-01
to 2025-12
to 2025-12
Research types:
Clinical research
Research areas:
Digestive system dysfunction
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS (IA-PACS-CFS)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Harald Pruess
Organisations:
Charité – University Medicine Berlin, German Center for Neurodegenerative Diseases (DZNE)
Research period:
2023-10
to 2025-02
to 2025-02
Research types:
Clinical research
Research areas:
Immune system dysfunction
Immunoadsorption vs Sham Treatment in Post-COVID-19 Patients With Chronic Fatigue Syndrome (EXTINCT post COVID)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Vega Goedecke
Organisations:
Hannover Medical School (MHH)
Research period:
2023-07
to 2025-06
to 2025-06
Research types:
Clinical research
Research areas:
Immune system dysfunction
Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS) (PoCoVIT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christiana Franke
Organisations:
Charité – University Medicine Berlin
Research period:
2023-10
to 2025-03
to 2025-03
Research types:
Clinical research
Research areas:
Immune system dysfunction, Nervous system dysfunction
Plasma cell targeting using the anti-CD38 antibody daratumumab in patients with ME/CFS – a randomized, placebo-controlled and double-blind phase II study
Project status:
Ongoing
Country:
Norway
Principal investigator:
Øystein Fluge
Organisations:
Haukeland University Hospital
Research period:
2025-06
to 2026-12
to 2026-12
Research types:
Clinical research
Research areas:
Immune system dysfunction
Prospective, exploratory, randomized, controlled, double-blind, phase IIa clinical trial in a cross-over design to evaluate the safety and tolerability and potential clinical effects of BC007 in patients with post-COVID syndrome
Project status:
Completed
Country:
Germany
Principal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
2023-10
to 2024-09
to 2024-09
Research types:
Clinical research
Research areas:
Immune system dysfunction
Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome (VERI-LONG)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Judith Bellmann-Strobl
Organisations:
Charité – University Medicine Berlin, Max Delbrück Center (MDC)
Research period:
2023-06
to 2025-04
to 2025-04
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction