Research types
This section of the ME/CFS Research Register beta version provides an overview of research types (types of medical research) connected with ME/CFS research. By clicking on one of the research types below, you will be directed to a separate page. There you will find research projects, areas, and networks, as well as working groups, selected people, and publications connected with the research type. You may also use the search function to look for specific topics or people, for example.
A description of the current scope of the ME/CFS Research Register beta version (e.g. which countries are included) can be found on the starting page.
Display count
26 of 26 research types
Search types
Basic research – Applied – Animal study
Description:
Applied basic research in which an animal model is used to better understand a condition and to uncover potential implications for the treatment in humans. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
1Basic research – Applied – Biochemistry
Description:
Applied basic research that explores the metabolic basis of a disease with the aim to understand the chemical processes unfolding within the human body. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
15Publications:
8Basic research – Applied – Cell study
Description:
Applied basic research that investigates how different cell types develop and how they affect the disease and potential treatments in patients. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
15Publications:
5Basic research – Applied – Genetics
Description:
Applied basic research that uses genetic engineering methods, including for the determination of genetic risk factors. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
1Publications:
1Basic research – Applied – Material development
Description:
Applied basic research centred around the development and improvement of analytical/diagnostic procedures for the determination of proteins, enzymes, markers or genes. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
5Publications:
1Basic research – Theoretical – Method developlment
Description:
Theoretical basic research used to support laboratory research. This includes computer models, improvement of imaging procedures and statistical analysis. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
0Clinical research – Interventional – Clinical trial phase I
Description:
Interventional clinical research as first step in drug development used to determine the safety and appropriate dosage of a drug. Subjects are usually healthy volunteers. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
0Clinical research – Interventional – Clinical trial phase II
Description:
Interventional clinical research that follows successful phase I trials. For drugs or treatments already approved for other diseases, phase II usually follows successful case reports/series. It involves a larger number of individuals and evaluates treatment efficacy as well as potential side effects. (Description adapted from:
Research projects:
4Publications:
1Clinical research – Interventional – Clinical trial phase III
Description:
Interventional clinical research that follows successful phase II study and includes an increase in the number of enrolled patients. Phase III trials seek to demonstrate the efficacy of an intervention in normal use and to establish more robust data on safety and side effects. A successful phase III is required for drug approval. (Description adapted from:
Research projects:
0Publications:
0Clinical research – Interventional – Clinical trial phase IV
Description:
Interventional clinical research that follow up after approval. Phase IV trials seek to understand the long-term impact and safety of an intervention. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
0Clinical research – Observational – Case report/series
Description:
Observational clinical research that includes retrospective detailed reporting of symptoms, diagnosis, treatment and follow-up of an individual or a series of individual patients that describes a novel form of diagnosis or treatment. (Description adapted from: https://www.aerzteblatt.de/archiv/64080...
Research projects:
0Publications:
4Clinical research – Observational – Diagnostic study
Description:
Observational clinical research that aims to evaluate the accuracy of a diagnostic test or method in identifying a disease entity. New biomarkers are examined for their diagnostic suitability via the characterisation of patients' disease profiles. (Description adapted from: https://www.aerztebla...
Research projects:
6Publications:
7Clinical research – Observational – Prognostic study
Description:
Observational clinical research that aims to evaluate a biomarker or diagnostic method with regards to its ability to predict the propability of remission or worsening of a condition. Patients are observed either spontaneously over time or during therapy. Biomarkers/diagnostic methods may be able to predict which therapy is most promising (Description adapted from:
Research projects:
3Publications:
1Clinical research – Observational – Therapy study
Description:
Observational clinical research in which patients are observed while a treatment is applied. In contrast to interventional clinical trials, the therapy regimen is adapted to the individual needs of the patient and does not follow a strict protocol. (Description adapted from: https://www.aerzteblatt....
Research projects:
5Publications:
4Epidemiological research – Interventional – Field/group study
Description:
Interventional epidemiological research based on field studies of a population in one location, or group studies covering specific individuals in a given population, e.g. a specific age group or patients with a certain disease. Health outcomes are measured dependent on a specific intervention. (Description adapted from:
Research projects:
5Publications:
2Epidemiological research – Observational – Case control study
Description:
Observational epidemiological research in which a group of individuals with disease is compared to individuals without disease in order to explore how health outcomes differ between both groups. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Fors...
Research projects:
5Publications:
16Epidemiological research – Observational – Cohort study
Description:
Observational epidemiological research in which a group of people/patients is recruited to explore their health in relation to specific variables. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
8Publications:
18Epidemiological research – Observational – Cross-sectional study
Description:
Observational epidemiological research applied to explore the occurrence of disease within a given population with the aim to determine the prelevance of the disease, representing a snapshot. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschu...
Research projects:
1Publications:
0Epidemiological research – Observational – Description with registry data
Description:
Observational epidemiological research in which registries collect data on the number of cases of a specific disease in time intervals. This information can be useful in examining the occurrence of a disease and in determining whether incidence and prevalence change over time. (Description adapted from:
Research projects:
0Publications:
0Epidemiological research – Observational – Monitoring/surveillance
Description:
Observational epidemiological research based on a systematic and continual oberservation of population health. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
0Secondary research – Meta Analysis – Systematic
Description:
Secondary research that provides a meta analysis based on statistical procedure, combining the results of several studies on the same question and calculating a more meaningful result. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)...
Research projects:
0Publications:
0Secondary research – Review – Guideline
Description:
Secondary research consisting of scientifically sound, practical recommendations, representing the evidence-based state of the art of a scientific field. (Description adapted from: https://www.egms.de/dynamic/en/guidelines/index.htm)
Research projects:
0Publications:
4Secondary research – Review – Hypothesis
Description:
Secondary research centred around a hypothesis article presents an idea that proposes a tentative explanation about a phenomenon or a narrow set of phenomena observed in science or medicine based on available evidence that may further be corroborated in the future. (Description adapted from: https://www.britannica.com/science...
Research projects:
0Publications:
6Secondary research – Review – Narrative
Description:
Secondary research review approach based on a selective narrative surrounding a specific research question. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientypen-in-der-medizinischen-Forschung)
Research projects:
0Publications:
14Secondary research – Review – Opinion
Description:
Secondary research that includes personal and original perspectives on a topic of interest to the general medical community. The aim is to stimulate debate or new research, cover controversial topics, or provide a new framework for, or interpretation of, an existing problem or current issue. (Description adapted from:
Research projects:
0Publications:
5Secondary research – Review – Systematic
Description:
Secondary research review approch that formulates a clearly defined research question and answer it using qualitative and quantitative methods. The goal is to analyse all available evidence in order to answer the question. (Description adapted from: https://www.aerzteblatt.de/archiv/64080/Studientyp...
Research projects:
0Publications:
5
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