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Research types

Clinical research - Observational - Diagnostic study

Description

Observational clinical research that aims to evaluate the accuracy of a diagnostic test or method in identifying a disease entity. New biomarkers are examined for their diagnostic suitability via the characterisation of patients' disease profiles. Description adapted from: https://www.aerzteblatt.de/int/archive/article/64227.

Research projects
18
Research areas
38
Research networks
4
Working groups
13
People
63
Publications
36
Event items
0

Research projects

Characterisation of brain function and vascular pathology with a focus on autonomic dysfunctions during sleep
Project status:
Ongoing
Country:
Germany
Principal investigator:
Robert Goeder
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Kiel
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Clinical characterisation, integrative morphological and functional studies of organ perfusion and biomarkers in patients with ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Wolfram Doehner
Organisations:
Charité – University Medicine Berlin, Berlin Institute of Health at Charité (BIH)
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Musculoskeletal system dysfunction, Nervous system dysfunction, Nutritional and metabolic system dysfunction, Cardiovascular system dysfunction
Endothelial Dysfunction and Altered Endothelial Biomarkers in Patients with Post-COVID-19 Syndrome and Chronic Fatigue Syndrome (ME/CFS)
Project status:
Completed
Country:
Germany
Principal investigator:
Milan Haffke
Organisations:
Charité – University Medicine Berlin, Max Delbrück Center (MDC), Berlin Institute of Health at Charité (BIH)
Research period:
Not available
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Endothelial Peripheral Arterial Tonometry (EndoPAT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin, Berlin School of Mind and Brain
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Evaluation of retinal vascular analysis as a diagnostic marker in post-infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christoph Schmaderer
Organisations:
University Hospital rechts der Isar (MRI TUM)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Functional autoantibodies against G-protein-coupled receptors in patients with ME/CFS (FAME)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Immune system dysfunction
Handgrip strength as a marker for muscular fatigue and fatigability in ME/CFS
Project status:
Completed
Country:
Germany
Principal investigator:
Bianka Jaekel
Organisations:
Charité – University Medicine Berlin, Berlin Institute of Health at Charité (BIH)
Research period:
Not available
Research types:
Clinical research
Research areas:
Musculoskeletal system dysfunction
Harmonisation and standardisation of the diagnosis of PEM in ME/CFS patients
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM), Technical University of Munich (TUM)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
General
Harmonised clinical phenotyping and biological signatures
Project status:
Ongoing
Country:
Germany
Principal investigator:
Martina Seifert
Organisations:
Charité – University Medicine Berlin
Research period:
2024-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction, General
Immune profiling and blood morphology analyses
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christian Puta
Organisations:
University Clinic Jena, Friedrich Schiller University Jena
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Immune system dysfunction, Musculoskeletal system dysfunction, Nervous system dysfunction
Investigating Cerebral Oxygen Metabolism Dysfunction as a pathomechanism of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Project status:
Ongoing
Country:
Austria
Principal investigator:
Lucas Haider
Organisations:
Medical University of Vienna
Research period:
2025-01
to 2026-02
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Mobile sleep studies in adolescents
Project status:
Ongoing
Country:
Germany
Principal investigator:
Insa Wolf
Organisations:
Fraunhofer Institute for Digital Media Technology (IDMT)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Multimodal characterisation of brain function and blood flow, neuronal metabolism and genetic risk structure
Project status:
Ongoing
Country:
Germany
Principal investigator:
Claudia Schilling
Organisations:
Central Institute of Mental Health (CIMH)
Research period:
2024-11
to 2027-11
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
Optical Coherence Tomography Angiography (OCT-A) and Non-invasive Dynamic Vessel Analysis (DVA)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin, Berlin School of Mind and Brain, Max Delbrück Center (MDC)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Cardiovascular system dysfunction
Skeletal Muscle Structure and Function in Relation to Post-exertional Malaise in Patients With PASC and ME/CFS
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Michele van Vugt
Organisations:
Amsterdam University Medical Center (Amsterdam UMC)
Research period:
2022-01
to 2025-12
Research types:
Clinical research
Research areas:
Musculoskeletal system dysfunction
Sodium Content in Lower Leg Muscle in Patients with ME/CFS
Project status:
Completed
Country:
Germany
Principal investigator:
Elisabeth Petter
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Clinical research
Research areas:
Musculoskeletal system dysfunction, Nutritional and metabolic system dysfunction
Structural and Functional MRI Studies and Accompanying Arterial Spin Labeling (ASL)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carsten Finke
Organisations:
Charité – University Medicine Berlin, Berlin School of Mind and Brain, Max Delbrück Center (MDC)
Research period:
2022-10
to not available
Research types:
Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction
The role of the skeletal muscle and myocardial metabolism in ME/CFS: in vivo MRS study.
Project status:
Ongoing
Country:
Austria
Principal investigator:
Martin Krssak
Organisations:
Medical University of Vienna
Research period:
2025-01
to 2026-03
Research types:
Clinical research
Research areas:
Musculoskeletal system dysfunction, Nutritional and metabolic system dysfunction, Cardiovascular system dysfunction

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