Basic research - Applied - Cell study
Description
Applied basic research that investigates how different cell types develop and how they affect the disease and potential treatments in patients. Description adapted from: https://www.aerzteblatt.de/int/archive/article/64227.
Research projects
32
Research areas
44
Research networks
7
Working groups
31
People
80
Publications
13
Event items
5
Research projects
Altered Endothelial Dysfunction‐related miRs in Plasma from ME/CFS Patients
Project status:
Completed
Country:
Austria
Principal investigator:
Francisco Westermeier
Organisations:
FH Joanneum University of Applied Sciences, Warsaw University of Technology
Research period:
Not available
Research types:
Basic research
Research areas:
Cardiovascular system dysfunction
Autoantibody-induced Transcriptome and Proteome as Biomarkers
Project status:
Ongoing
Country:
Germany
Principal investigator:
Gabriela Riemekasten
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Luebeck
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Luebeck, University Hospital rechts der Isar (MRI TUM), Charité – University Medicine Berlin, Max Delbrück Center (MDC), Technical University of Munich (TUM)
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, General
Brain changes in ME/CFS: Focus on the stress and immune system
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Inge Huitinga
Organisations:
Vrije Universiteit Amsterdam (VU Amsterdam), Netherlands Institute for Neuroscience (NIN), University of Amsterdam
Research period:
2023-01
to 2027-12
to 2027-12
Research types:
Basic research
Research areas:
Nervous system dysfunction
Cell Morphology, Cell Deformability and Microclots in ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Annick Fehrer
Organisations:
Charité – University Medicine Berlin, Max Planck Institute for the Science of Light
Research period:
2024-01
to 2026-12
to 2026-12
Research types:
Basic research
Research areas:
Hemic and lymphatic system dysfunction, Infections
Chronic Fatigue Syndrome and Immunedeficiencies
Project status:
Completed
Country:
Austria
Principal investigator:
Eva Untersmayr-Elsenhuber
Organisations:
Medical University of Vienna
Research period:
2019-03
to not available
to not available
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Clinic and granulocytes
Project status:
Ongoing
Country:
Germany
Principal investigator:
Alexander Dejaco
Organisations:
University Clinic Regensburg
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Cardiovascular system dysfunction, General
Clinic, HDL proteome, and AI
Project status:
Ongoing
Country:
Germany
Principal investigator:
Elisabeth Schieffer
Organisations:
University Clinic Giessen and Marburg
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction
Clinical and immunological phenotyping and analysis of EBV autoantigens and autoantigens
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM), Technical University of Munich (TUM)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Clinical and immunological phenotyping, analysis of autoantigens and T and B cell communication
Project status:
Ongoing
Country:
Germany
Principal investigator:
Birgit Sawitzki
Organisations:
Charité – University Medicine Berlin, Berlin Institute of Health at Charité (BIH)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Clinical characterisation for biomarker discovery
Project status:
Ongoing
Country:
Germany
Principal investigator:
Helena Radbruch
Organisations:
Charité – University Medicine Berlin
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction
Clinical characterisation, integrative morphological and functional studies of organ perfusion and biomarkers in patients with ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Wolfram Doehner
Organisations:
Charité – University Medicine Berlin, Berlin Institute of Health at Charité (BIH)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Musculoskeletal system dysfunction, Nervous system dysfunction, Nutritional and metabolic system dysfunction, Cardiovascular system dysfunction
Decreased NO Production in Endothelial Cells Exposed to Plasma from ME/CFS Patients
Project status:
Completed
Country:
Austria
Principal investigator:
Jennifer Blauensteiner
Organisations:
FH Joanneum University of Applied Sciences
Research period:
Not available
Research types:
Basic research
Research areas:
Cardiovascular system dysfunction
EBV, SARS-CoV-2, HSV Mimicry Epitopes and Autoantibodies
Project status:
Ongoing
Country:
Germany
Principal investigator:
Franziska Sotzny
Organisations:
University Hospital rechts der Isar (MRI TUM), Charité – University Medicine Berlin, Technical University of Munich (TUM), Helmholtz Munich
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction, General
Evaluation of the link between auto-immunity and derangements in immune cell metabolism and function in ME/CFS (EnergiseME)
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Niels Eijkelkamp
Organisations:
University Medical Centre Utrecht (UMC Utrecht)
Research period:
2023-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nutritional and metabolic system dysfunction
Evidence and Effect of Serum Factors in Patients with ME/CFS after COVID-19 on Endothelial Cell Function In Vitro
Project status:
Ongoing
Country:
Germany
Principal investigator:
Kanchan Dulal
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Cardiovascular system dysfunction
Explaining skeletal muscle-related symptoms in patients with ME/CFS: from skeletal muscle to exercise immunology (MuscleME)
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Rob Wust
Organisations:
Vrije Universiteit Amsterdam (VU Amsterdam)
Research period:
2023-01
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Hemic and lymphatic system dysfunction, Musculoskeletal system dysfunction
HHV-6 Mediated Mitochondrial Modulation and Its Association to ME/CFS
Project status:
Completed
Country:
Latvia, Germany
Principal investigator:
Bhupesh K. Prusty
Organisations:
Charité – University Medicine Berlin, University Clinic Erlangen, University of Wuerzburg, University of California San Diego, Riga Stradins University
Research period:
Not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction, General
Harmonised clinical phenotyping and biological signatures
Project status:
Ongoing
Country:
Germany
Principal investigator:
Martina Seifert
Organisations:
Charité – University Medicine Berlin
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research, Clinical research
Research areas:
Nervous system dysfunction, Cardiovascular system dysfunction, General
Immune Aberrations in Post-Infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anna Aschenbrenner
Organisations:
University Clinic Bonn, Charité – University Medicine Berlin, German Center for Neurodegenerative Diseases (DZNE)
Research period:
2022-08
to 2025-07
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Impact of the serum of Post-COVID-Syndrome patients without vs with ME/CFS on endothelial cell function
Project status:
Completed
Country:
Germany
Principal investigator:
Lavinia Flaskamp
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Cardiovascular system dysfunction
Infectious Triggers and Mitochondrial Dysfunction in ME/CFS
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2021-08
to not available
to not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction
Insights into immune cell infiltration and mast cell activation in post-exertional malaise in post-COVID
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Rob Wust
Organisations:
Vrije Universiteit Amsterdam (VU Amsterdam)
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction, Musculoskeletal system dysfunction
Integrative data analyses of human and animal model samples for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Volker Bruns
Organisations:
Fraunhofer Institute for Integrated Circuits (IIS)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction, General
Integrative transcriptome analyses of human and animal model samples for ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Emanuel Wyler
Organisations:
Max Delbrück Center (MDC)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Immune system dysfunction, Nervous system dysfunction, Endocrine system dysfunction, General
Investigation of PEM and ME/CFS-associated tryptophan metabotypes
Project status:
Ongoing
Country:
Germany
Principal investigator:
Konrad Aden
Organisations:
University Clinic Schleswig-Holstein (UKSH) - Kiel, Kiel University (CAU)
Research period:
2024-11
to 2027-11
to 2027-11
Research types:
Basic research
Research areas:
Nutritional and metabolic system dysfunction
Muscle microclots and microvascular pathology in ME/CFS
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Rob Wust
Organisations:
Vrije Universiteit Amsterdam (VU Amsterdam)
Research period:
2024-07
to not available
to not available
Research types:
Basic research
Research areas:
Hemic and lymphatic system dysfunction, Musculoskeletal system dysfunction
Relevance of Raman spectroscopic signatures from blood cells in ME/CFS diagnostics
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anuradha Ramoji
Organisations:
Leibniz Institute of Photonic Technology
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction, Musculoskeletal system dysfunction
The impact of mast cell activation on epithelial and endothelial barrier dysregulation in post-infectious ME/CFS (DegranulateME)
Project status:
Ongoing
Country:
Austria
Principal investigator:
Eva Untersmayr-Elsenhuber
Organisations:
FH Joanneum University of Applied Sciences, Medical University of Vienna
Research period:
2025-01
to 2025-12
to 2025-12
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction, Nutritional and metabolic system dysfunction, General
The molecular immune signature in ME/CFS as stratification tool for future personalized treatment (IMMUNESTRATIFY)
Project status:
Ongoing
Country:
Netherlands
Principal investigator:
Willem A. Dik, Marjan Versnel
Organisations:
Erasmus Medical Center (Erasmus MC), Erasmus University Rotterdam
Research period:
2023-01
to 2027-12
to 2027-12
Research types:
Basic research
Research areas:
Immune system dysfunction
Understanding Potential Infectious Triggers and Mitochondrial Dysfunction in ME/CFS
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2025-01
to not available
to not available
Research types:
Basic research
Research areas:
Infections, Nutritional and metabolic system dysfunction
Unraveling Endothelial Function in ME/CFS
Project status:
Ongoing
Country:
Austria
Principal investigator:
Francisco Westermeier
Organisations:
FH Joanneum University of Applied Sciences, Warsaw University of Technology, Medical University of Graz
Research period:
Not available
Research types:
Basic research
Research areas:
Cardiovascular system dysfunction