Plasma Extracellular Vesicles as Potential Biomarkers for Endothelial Dysfunction in ME/CFS

Project description

The project aims to identify new biomarkers for ME/CFS from blood plasma. The researchers plan to isolate extracellular vesicles (EVs) from the plasma of ME/CFS patients as well as healthy subjects. These EVs will then be examined with regard to their characteristic spectrum of candidate molecules, such as microRNAs and proteins, as potential biomarkers for endothelial dysfunction. The discovery of such EV biomarkers could not only lead to an improved diagnosis, but also contribute to an expanded understanding of the underlying disorder of vascular function and the pathophysiology of ME/CFS.

(Description adapted from project website: see link above)