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Immune system dysfunction

Description

Immune system is the body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components. Diseases of the immune system are disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both. (Description adapted from https://www.ncbi.nlm.nih.gov/mesh/68007154 and https://www.ncbi.nlm.nih.gov/mesh/68007107)

Research projects
16
Research types
18
Research networks
3
Working groups
8
People
48
Publications
44
Event items
3

Research projects

Analysing Antibody Responses against EBV-derived Antigens in ME/CFS
Project status:
Completed
Country:
Poland, UK, Germany
Principal investigator:
Carmen Scheibenbogen, Nuno Sepúlveda
Organisations:
Charité – University Medicine Berlin,Warsaw University of Technology
Research period:
2020-10
to not available
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Autoantibody-induced Transcriptome and Proteome as Biomarkers
Project status:
Ongoing
Country:
Germany
Principal investigator:
Gabriela Riemekasten
Organisations:
University Clinic Schleswig-Holstein - Luebeck (UKSH)
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Autoimmunity Risk Variants in the PTPN22 and CTLA4 Genes are Associated with Infectious Onset of ME/CFS
Project status:
Completed
Country:
Germany
Principal investigator:
Sophie Steiner
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction, Genetic risk factors, General
Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Clinic Schleswig-Holstein - Luebeck (UKSH),Charité – University Medicine Berlin,University Hospital rechts der Isar (MRI TUM),Max Delbrück Center (MDC),Technical University of Munich (TUM)
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, General
Chronic Fatigue Syndrome and Immunedeficiencies
Project status:
Completed
Country:
Austria
Principal investigator:
Eva Untersmayr-Elsenhuber
Organisations:
Medical University of Vienna
Research period:
2019-03
to not available
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction
Development of Diagnostic Tests to Detect Autoantibodies in CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction
EBV, SARS-CoV-2, HSV Mimicry Epitopes and Autoantibodies
Project status:
Ongoing
Country:
Germany
Principal investigator:
Franziska Sotzny
Organisations:
Charité – University Medicine Berlin,University Hospital rechts der Isar (MRI TUM),Technical University of Munich (TUM),Helmholtz Munich
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Infections, Immune system dysfunction, General
Establishing Immunological Assays for the Diagnostics of ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Annick Fehrer
Organisations:
University Clinic Bonn,Charité – University Medicine Berlin,German Center for Neurodegenerative Diseases (DZNE)
Research period:
Not available
Research types:
Basic research
Research areas:
Immune system dysfunction
Immune Aberrations in Post-Infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anna Aschenbrenner
Organisations:
University Clinic Bonn,Charité – University Medicine Berlin,German Center for Neurodegenerative Diseases (DZNE)
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS (IA-PACS-CFS)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Harald Pruess
Organisations:
Charité – University Medicine Berlin,German Center for Neurodegenerative Diseases (DZNE)
Research period:
2023-10
to 2025-02
Research types:
Clinical research
Research areas:
Immune system dysfunction
Immunoadsorption vs Sham Treatment in Post-COVID-19 Patients With Chronic Fatigue Syndrome (EXTINCT post COVID)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Vega Goedecke
Organisations:
Hannover Medical School (MHH)
Research period:
2023-07
to 2025-06
Research types:
Clinical research
Research areas:
Immune system dysfunction
Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS) (PoCoVIT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christiana Franke
Organisations:
Charité – University Medicine Berlin
Research period:
2023-10
to 2025-03
Research types:
Clinical research
Research areas:
Immune system dysfunction, Nervous system disorder
Mitochondrial Dysfunction and Metabolic Changes
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2022-08
to 2025-07
Research types:
Basic research
Research areas:
Immune system dysfunction, Nutritional and metabolic system disorder
Observational Study of the Effect of Immunoadsorption (IA) in Patients < 18 Years of Age with ME/CFS with Evidence of Autoantibodies (BIAKI)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Wolfgang Ries
Organisations:
DIAKO Hospital
Research period:
2023-11
to 2025-11
Research types:
Clinical research
Research areas:
Immune system dysfunction
Repeat Immunoadsorption Post Covid ME/​CFS (RIA)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
2022-08
to 2025-01
Research types:
Clinical research
Research areas:
Immune system dysfunction
unCOVer Erlangen - ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
Not available
Research types:
Clinical research
Research areas:
Immune system dysfunction