ME/CFS Research Foundation Logo

Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics

About

Status:
Ongoing
Principal investigator:
Country:
Germany
Study start:
2022-07-31
Completion (planned):
2025-07-30
Last update:
2023-11-30

 

Research types:
Basic research
Research areas:
Immunological dysfunction, General
Interventions:
Not applicable
Priv. Sector Partner:
Sponsors:

Project description

This project of the Immune Mechanisms of ME (IMMME) research network will provide biospecimens and clinical data from well-established cohorts of patients with post-infectious ME/CFS or autoimmune diseases with overlapping symptoms to ME/CFS, as well as age- and sex-matched healthy controls. The biosamples are made available to the various experimental studies within the IMMME network. Autoantibodies against GPCR are determined using certified ELISA tests (CellTrend). With the help of bioinformatics/biostatistics, clinical and experimental data from the various IMMME projects are linked together in order to identify connections and understand disease mechanisms.

(Description adapted from project website: see link above)

Patient cohort

ME/CFS according to Canadian Consensus Criteria (CCC) compared with autoimmune diseases and healthy controls.

Patients enrolled: Not available

Age group: Not available

Research areas (6)
Research types (2)
Research networks (1)
Working groups (5)
People (7)
Publications (0)
Organisations (4)

Research areas

Immunological dysfunction
Description:
Immune system is the body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components. Diseases of the immune system are disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-m...
Research projects:
17
Publications:
39